The Bills enter the game 10-2 and have a healthy lead atop the AFC East, but are battling the Kansas City Chiefs (11-1) for the top playoff seed in the AFC. The Rams, meanwhile, are 6-6 and in the middle of a tough playoff race in the NFC West, with all four teams within two games of each other in the standings.
Tom Brady is on the call for the game, providing insight from the booth, while FOX Sports NFL writer Henry McKenna shares his analysis live throughout this game.
Check out below for all the biggest plays from the game.
1:54p ET
Live scoreboard
7:38a ET
Bills sneak in a late score, but unable to get the onside kick
7:22a ET
A big fourth-down conversion and creative screen help extend Rams’ lead
7:06a ET
Josh Allen scores his 5th total TD to cut Rams’ lead to 3
6:54p ET
Josh Allen responds to cut the Rams’ lead to 10 again
6:45p ET
Cooper Kupp comes up with a thigh (!) TD catch in double coverage
6:28p ET
Bills aren’t going away
6:24p ET
LA’s rushing attack is doing its job
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6:19p ET
Rams open up their biggest lead
5:50p ET
Halftime: Rams secondary is keeping Josh Allen in check
5:35p ET
Rams WRs deserve more love
5:27p ET
Puka Nacua makes ‘unbelievable’ sideline catch
5:18p ET
Bills offense brings the fireworks
5:15p ET
Rams wow with a huge blocked punt return TD
5:08p ET
LA remains committed to the run
5:01p ET
Is Khalil Shakir the Bills’ Julian Edelman?
4:50p ET
Josh Allen answers right back
4:39p ET
The Rams run right down the field
1:54p ET
Preview: Bills, Rams both eye improved playoff position, just from different angles
Live Coverage for this began on 7:40a ET
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