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BigPaulSports > Blog > Game Analysis > 2025 NFL Comeback Player of the Year Odds: Christian McCaffrey New Favorite
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2025 NFL Comeback Player of the Year Odds: Christian McCaffrey New Favorite

BigP
Last updated: 2025/11/04 at 9:43 PM
BigP Published November 4, 2025
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2025 NFL Comeback Player of the Year Odds: Christian McCaffrey New Favorite
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Everybody loves a comeback story.

Last season, Cincinnati’s Joe Burrow took home the Comeback Player of the Year award. As a matter of fact, he’s one of only two players ever to win the award twice. 

Burrow missed the last seven games of the 2023 season after suffering a wrist injury. In his comeback campaign, he passed for 4,918 yards and 43 touchdowns, and both were best in the NFL.

So who takes home the hardware for the 2025-26 season? Let’s look at the latest odds at DraftKings Sportsbook as of Nov 4.

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

AP Comeback Player of the Year 2025-26

Christian McCaffrey, RB, 49ers: -110

What to know: McCaffrey is the new favorite in this spot, moving to -110 from +250 over the last three weeks. He played in four games last season before suffering a season-ending right knee injury. This year, he is leading the NFL in carries through six weeks (168). Additionally, the dual-threat back has 596 rushing yards, four rushing TDs, 626 receiving yards and four receiving TDs on the season.

Dak Prescott, QB, Cowboys: +130

What to know: Prescott played eight games in 2024 before being sidelined with a hamstring injury. This season, he’s completing 75.2% of his passes (third in NFL) for 2,319 yards (fourth) and 17 touchdowns (T-third).

Aidan Hutchinson, DE, Lions: +450 

What to know: In Week 6 of last season, Hutchinson fractured the tibia and fibula in his left leg and missed the remainder of the season. He was back for the start of this season, and he has seven sacks (T-sixth) and four forced fumbles (T-first) on the year.

Daniel Jones, QB, Giants: +750

What to know: Jones didn’t get injured last season. Instead, he was benched and then released by the Giants after Week 10, with the Giants sitting at 2-8 and Jones tallying eight TDs and seven interceptions. This season, he appears reborn with the Colts. Jones has helped lead Indy to a 7-2 record. His 2,404 passing yards are best in the NFL and he has a QBR of 70.6.

J.J. McCarthy, QB, Vikings: +2500

What to know: J.J. McCarthy’s rookie season in 2024 ended before it even began. He underwent surgery to repair a torn meniscus in August of last year before ever taking a snap in the regular season. And while he’s had some injury setbacks this season, he’s shown flashes of high potential when available. In three appearances, he has 444 passing yards, four TDs through the air and two rushing touchdowns.

Trevor Lawrence, QB, Jaguars: +2800 

What to know: Lawrence started 10 games last season before missing the final seven games of the season after suffering a concussion in Week 10. In those 10 games, the Jags were 2-8. This season, however, they are 5-3 after 9 weeks and Lawrence has 1,840 passing yards and nine touchdowns. His odds in this spot have dipped over the last three weeks, dropping to +2800 from +1500.

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TAGGED: nfl
BigP November 4, 2025
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